PMOS (polyendocrine metabolic ovarian syndrome)
PMOS is a common hormonal condition that can affect your periods, your skin and hair, your weight, and how you feel. It cannot be cured, but there is a lot that can be done to manage it and to lower the longer-term health risks. Dr Anu Mahadik helps you understand what is happening and works with you on a plan that fits your goals. She consults at Westmead and Kogarah.
A note on the name
PCOS is now called PMOS
For many years, this condition was called polycystic ovary syndrome, or PCOS. In 2026, experts around the world agreed on a new name: polyendocrine metabolic ovarian syndrome, or PMOS. You may still see the old name in many places, and lots of people still know it as PCOS.
Having polycystic-looking ovaries on an ultrasound on its own does not mean you have PMOS. Many people have this appearance without the condition. PMOS can affect you at any stage of your reproductive life, from the teenage years through to menopause.The name was changed because the old one was misleading. It suggested the condition is mainly about cysts on the ovaries, but that is not the case. Research has confirmed there is no increase in harmful cysts on the ovaries, and the condition affects much more than the ovaries alone. The new name reflects that it involves several hormone systems (polyendocrine), the way the body handles insulin and weight (metabolic), and the ovaries.
The change is being rolled out worldwide over a few years, so you will hear both names for some time. If you were told you have PCOS, you have what is now called PMOS. Nothing about your diagnosis or your care has changed because of the name.
Overview
Understanding PMOS
What PMOS is
Polyendocrine metabolic ovarian syndrome (PMOS) is a common hormonal condition. Despite the name, it is not really a problem of the ovaries, and it does not involve true cysts. It is better understood as a condition with four sides to it: it can affect your periods and fertility, how your body handles insulin and weight, your skin and hair, and your emotional wellbeing. Because it works in several ways at once, care looks at the whole picture rather than one symptom on its own.
Having polycystic-looking ovaries on an ultrasound on its own does not mean you have PMOS. Many people have this appearance without the condition. PMOS can affect you at any stage of your reproductive life, from the teenage years through to menopause.
How common it is
PMOS is one of the most common hormonal conditions in women, affecting about 1 in 8 women in Australia. It is still often missed or diagnosed late, partly because the symptoms vary so much from person to person. If you recognise some of the signs below, it is worth talking to a doctor.
Symptoms
Signs and symptoms of PMOS
PMOS looks different in each person. Some people have only mild signs, while others have several. Symptoms often fall into a few groups.
Periods and cycle changes
- Periods that are irregular, infrequent, or absent
- Difficulty falling pregnant, which is linked to less frequent ovulation
Skin and hair changes
- Excess hair on the face or body (hirsutism)
- Acne
- Thinning hair or hair loss from the scalp
Weight and metabolic changes
- Weight gain, or difficulty losing weight
- Signs linked to insulin resistance, where the body has to make more insulin than usual
Not everyone with PMOS has weight gain or insulin problems, and you do not need every symptom to have the condition. Low mood, anxiety, and the impact on day-to-day life are also common and are taken seriously as part of care.
Diagnosis
How PMOS is diagnosed
There is no single test for PMOS. It is diagnosed by looking at your symptoms together with some tests, and by ruling out other conditions that can cause similar signs. It can take time to reach a diagnosis, which many people find frustrating.
The tests Dr Mahadik may arrange
Depending on your situation, this may include:
- Blood tests to check hormone levels, including testosterone and other hormones that can cause similar symptoms, such as thyroid hormones and prolactin
- Blood tests to check how your body handles sugar and to look at cholesterol, as PMOS is linked to insulin resistance
- An ultrasound of the ovaries, in some cases
A pelvic ultrasound is often done through the vagina (a transvaginal ultrasound) so the ovaries can be seen clearly. This is discussed with you first, and it is your choice.
How the diagnosis is made
For adults, a diagnosis of PMOS is made when at least two of the following three features are present, and other causes have been ruled out:
- Irregular or absent periods (a sign that ovulation is not happening regularly)
- Signs of higher androgen ("male-type" hormone) levels, either on a blood test or from symptoms such as excess hair or acne
- Ovaries that show many small follicles on ultrasound — sometimes called polycystic-looking ovaries — or a raised level of a hormone called AMH (anti-Müllerian hormone) on a blood test. Despite the old name, these are not harmful cysts, and this finding on its own does not mean you have PMOS.
Under the current Australian-led guideline, an AMH blood test can now be used as an alternative to ultrasound in adults. And if you already have both irregular periods and clear signs of higher androgen levels, neither an ultrasound nor an AMH test is needed to confirm the diagnosis. Diagnosis in teenagers is more careful, because irregular cycles and some other features can be a normal part of puberty.
Managing PMOS
How PMOS is managed
PMOS cannot be cured, but it can be managed well. There is no single treatment, because the right plan depends on your symptoms, your general health, and whether you are hoping to become pregnant. Care usually combines healthy-lifestyle steps with treatment aimed at the symptoms that bother you most. Do not start or stop a prescribed medicine without medical advice.
Healthy lifestyle
A healthy lifestyle is the foundation of PMOS care at every stage of life. Regular activity and balanced eating can help with insulin resistance, cycle regularity, and general wellbeing, and they lower long-term health risks. No single diet or exercise plan works best for everyone, so the aim is a pattern you can keep up. People with PMOS can find weight harder to shift, because of the hormone changes involved. So support is focused on health, not on a number on the scales.
Periods and protecting the lining of the uterus
When periods are very infrequent, the lining of the uterus is not shed regularly, which over many years can raise the risk of changes in the lining. Bringing on regular bleeds helps protect it. The combined pill is a common first choice for managing irregular periods and for helping with acne and excess hair. A hormonal intrauterine device is another option that protects the lining. Which option suits you depends on your symptoms and your plans, and it is worth talking through.
Excess hair and skin changes
Excess hair and acne can be helped by the combined pill, and, where needed, by anti-androgen medicines that lower the effect of male-type hormones. These treatments take a few months to show their full effect. Some people also choose cosmetic options for hair, such as laser, waxing, or shaving, alongside or instead of medicine.
Insulin and metabolic health
Metformin, a medicine also used in diabetes, can help the body respond to insulin. It may also support cycle regularity, particularly when the combined pill is not suitable. It is used mainly for the metabolic side of PMOS rather than as a weight-loss treatment. Some people ask about inositol, a supplement; the current evidence for a clear benefit is limited, so it is worth discussing before spending money on it.
Emotional wellbeing
PMOS can affect how you feel, and rates of low mood and anxiety are higher in people with the condition. This is a recognised part of PMOS, not a personal failing. Dr Mahadik can check in on how you are coping. If it would help, your GP can arrange a mental health care plan. This gives access to Medicare-rebated sessions with a psychologist. You do not have to manage the emotional side on your own.
PMOS and fertility
PMOS and getting pregnant
Many people with PMOS have children. Because ovulation can be less regular, it can take longer to fall pregnant, but there is a lot that can help.
For those hoping to conceive, a healthy lifestyle comes first. Even a modest weight loss, around 5 to 10 per cent of your body weight, can help restore ovulation for some people. If that is not enough, a medicine can be used to encourage the ovaries to release an egg. Under the current guideline, letrozole is the preferred first medicine for this, and other options may be considered if needed. Some people go on to have treatment such as IVF. Ovulation-inducing medicines and IVF are provided through a specialist fertility service, and Dr Mahadik can discuss your options and referral.
Long-term health
Looking after your long-term health
PMOS is a lifelong condition, and managing it well is not only about today's symptoms. Over time, PMOS is linked to a higher chance of some other health conditions, which is why regular check-ups matter. These include type 2 diabetes, high blood pressure and heart health, changes in the lining of the uterus when periods are very infrequent, and sleep apnoea. The good news is that the steps that help your symptoms also help lower these risks. That means staying active, looking after your weight, and having regular reviews. Dr Mahadik can keep an eye on the things worth watching and adjust your plan as your life changes.
Common questions
PMOS — common questions
PMOS — polyendocrine metabolic ovarian syndrome — is a common hormonal condition that can affect your periods, fertility, skin and hair, weight, and mood. Despite the name, it is not really a problem of the ovaries and does not involve true cysts. It affects about 1 in 8 women in Australia.
Yes. PMOS (polyendocrine metabolic ovarian syndrome) is the new name for the condition that used to be called PCOS (polycystic ovary syndrome). They are the same condition. The name was changed in 2026 to describe it more accurately. If you were diagnosed with PCOS, you have what is now called PMOS, and your care is the same.
The old name suggested the condition was mainly about cysts on the ovaries. Research has shown this is not the case — there is no increase in harmful cysts, and the condition affects several hormone systems, the way the body handles insulin and weight, and more. Experts around the world, led from Australia, agreed on the new name, polyendocrine metabolic ovarian syndrome (PMOS), so the name reflects what the condition really is. The change is being introduced over a few years.
No. Having polycystic-looking ovaries on an ultrasound on its own does not mean you have PMOS. Many people have this appearance without the condition. A diagnosis looks at your symptoms and other tests together, and rules out other causes.
PMOS cannot be cured, as it is a lifelong condition, but it can be managed well. Managing it also lowers the longer-term health risks linked to PMOS. The right plan depends on your symptoms and whether you are hoping to become pregnant.
There is no single test. Diagnosis usually involves blood tests to check hormone levels and how your body handles sugar, sometimes an ultrasound of the ovaries, and ruling out other conditions with similar symptoms. A GP referral is needed to see Dr Mahadik, who can arrange the right tests.
Yes. A GP referral is needed to see Dr Mahadik, and it also means your appointment may attract a Medicare rebate. Your GP can start some initial checks and refer you to Dr Mahadik in Sydney at either location.
The combined pill is a common first choice, as it helps regulate periods and can also improve acne and excess hair. A hormonal intrauterine device is another option that protects the lining of the uterus. Metformin may help in some situations, especially where the pill is not suitable. Weight loss and regular activity can also help some people regain more regular cycles. Hormonal options are not used while you are trying to conceive.
The combined pill can help, and anti-androgen medicines may be added where needed. These take a few months to show their full effect. Some people also choose cosmetic options for hair, such as laser, waxing, or shaving. Your GP referral lets Dr Mahadik talk through what suits you.
PMOS is linked to insulin resistance, which over time can raise the risk of type 2 diabetes, but it is not certain that you will develop it. Regular activity, balanced eating, and check-ups help lower the risk. Metformin is sometimes used to support how your body handles insulin. Regular blood tests can track your glucose over time.
Low mood and anxiety are more common in people with PMOS, and this is a recognised part of the condition rather than a personal failing. If it would help, your GP can arrange a mental health care plan for Medicare-rebated sessions with a psychologist. It is worth raising, as support is available.
Many people with PMOS have children. It may take longer to fall pregnant because ovulation can be less regular. A healthy lifestyle helps, and a modest weight loss of around 5 to 10 per cent of body weight can restore ovulation for some people. If needed, a medicine such as letrozole can encourage ovulation, and some people go on to have IVF through a specialist fertility service. Dr Mahadik can discuss your options and referral.
Fees vary by appointment type, and a GP referral means your consultation may attract a Medicare rebate. For current fees, please contact the rooms.
Take the next step in managing your PMOS
Whether your main concern is your periods, your skin, your weight, or planning a pregnancy, a review can help you understand what is going on and build a plan that fits you. Dr Mahadik will talk it through at a pace that feels comfortable.